None of which has anything to do with the OP's issue. Also none of which have anything to do with how the aircraft flies. I'm simply pointing out that helicopter mode is certainly capable of operating the aircraft, with given cons.
proper channels working? Using JR 12x and JR 9503 radios I've never had an issue getting proper channels working, I see no difference here in air vs heli mode.
preset mix that is useless in a multirotor? As I alluded to, you DO lose the ability to use the Aux 1 channel to program for some other function. With a minimal radio (6 or 7 channel), this could be a deal breaker.
proper layout on LCD Screen? Not sure how this is a factor, may be specific to YOUR radio, mine all look the same regardless of mode.
proper timer? Again may be radio specific, the JR radio can be setup for throttle up turns timer on. In either mode....
In most cases, I agree airplane mode is better due to the aux 1 issue. Otherwise, no difference. I would like to take a peek at the new "multirotor" programming in the new Futaba Radios, looking at getting a 14 SG myself!
BTW, I have a couple of large rigs myself...