ok sorry, 5000Mah 4S lipo 45-90 discharge 30A ESC Sunnysky 2814 700KV motors the power distribution board is a 100A
You should stick with 10AWG from battery to PDB - maximum load will be approaching 100Amps, way too much for 16AWG. It's always better to play safe with wire sizes - getting it wrong could, at best, shorten your flight time or, at worst, turn your quad into a flaming 4kg projectile that can punch through someone's roof and set fire to their home.
What worries me (and I apologise for coming across harsh) is that you are asking this question at all - "...can I use 16AWG...?" - why 16AWG in particular? Because it "fits"? Because you
have some? I'd have been much more relaxed if you'd asked "how do I calculate the correct wire gauge to use?"